MD, PhD, Lecturer – Department of Medical Genetics – University of Medicine
and Pharmacy “Carol Davila” Bucharest, Romania
General Manager – “Alco San” Medical Clinic Bucharest, Romania
Medical Competences: Oculo – Orbitar Ultrasound Examination and
Awards and Recognition:
– iERP Awards 2019 – Excellence in Medical Genetics
– TOP 100 Scientists – 2018, IBC Great Britain, 2018
Dental anomalies are craniofacial abnormalities of form, function, or position of
the teeth, bones, and tissues of the jaw and mouth.
The National Institute of Dental and Craniofacial Research (NIDCR) estimates
that in the United States a baby is born every hour with a craniofacial defect (1).
Genetics plays a very important role in normal craniofacial development, abnormal
dental anomalies, and different dental diseases such as dental caries,
periodontitis, and dental malocclusion (2).
The most common problems in dentistry are dental caries, periodontal problems,
dental anomalies, and malocclusion. Mainly a multifactorial etiology for all the
conditions are there, but most of the times genetic condition prevails (3).
The genetic causes of dental pathologies are multiple. Phenotype and severity is
dependent on the affected gene, the type and location of the mutations (4).
Dental anomalies can range from missing or stained teeth to cleft palates. Many
are expressions of other, more complex disorders (1).
We still do not know all the causes of the dental diseases, but their genetic basis is
not a neglected factor (4).
Genetic counseling, mapping, and testing can help prevent dental anomalies in
the next generation of children (1).