Book Description

The beginning of 2021 has seen outbreaks of novel coronavirus COVID-19 infections, which have become a global pandemic. It is considered to have higher contagiousness and mortality compared to SARS and MERS. Clinical manifestations of nCOVID-19 symptoms are identied as coughs, fevers, vomiting, chills, joint pain, shortness of breath, and diarrhea. Older people over 70 years of age and those with chronic debilitating diseases such as end-stage illness, diabetes mellitus, hypertension, and pulmonary diseases are at a higher risk of mortality from nCOVID-19 infection. Currently, no specic approved antiviral drugs are available against nCOVID-19. Considering this imminent need, scientists and physicians have been racing to better understand this new pandemic virus-specic mechanism, pathophysiology, and target site of the disease to nd effective therapeutic agents and vaccines. This review summarized the origin, transmission, clinical symptoms, and conventional outcome treatment strategies of infection. It also included a discussion of the potential for recurrence. In our study, we emphasized reported potential repurposing drugs that are effective against SARS, MERS, and nCOVID-19, among other diseases. Our early knowledge will provide an overview of the intelligence basis work for currently existing therapeutic vaccines against nCOVID-19 that will be useful in the development of future vaccines. Preventive interventions and early diagnosis of nCOVID-19 outbreaks should be implemented immediately in order to reduce the disease burden both locally and worldwide.