MEDICAL SCIENCE
Laboratory Animals And Experimentation
by Dr. A. Padmaraj
ISBN Number : 978 - 93 - 91478 - 59 - 9
Authors Details
| Author Name | Image | About Author |
|---|---|---|
| Dr. A. Padmaraj |  |
Dr. Appavu Padmaraj did his Bachelor and Master degrees in Veterinary Science from the legendary
Madras Veterinary College and worked as Research Ofcer in the Institute of Veterinary Preventive
Medicine (a unit of Department of Animal Husbandry, Govt. of Tamil Nadu) at Ranipet. After
completing 30 years of service, he quit the job and served as Senior Scientist in M/s. Bio-Med Private
Ltd., Ghaziabad (U.P.), a Human and Veterinary Vaccines Institute and then as Animal
Experimentation In-Charge at M/s. BIOVET Private Ltd., Malur (Karnataka), a Veterinary Vaccines
Institute In 2018, he took up the position of Veterinary Ofcer in Biomedical Research Unit and
Laboratory Animal Centre at Saveetha Dental College (afliated to Saveetha Deemed University),
Chennai. Since 2020, he is utilizing his four decades of experience and expertise in writing books and offering assistance to
researchers and students. Dr. Padmaraj has rich experience in Vaccine Production, Quality Control, Animal Experimentation,
Animal Disease Investigation, Animal Facility Design and Maintenance besides related R&D work. He conducted Orientation
& Hands-On Training programs and prepared course materials for Animal Tissue Culture courses for research personnel and
employees. He has published 25 Research Papers in reputed Indian Journals. |
| Dr. Devaraj Ezhilarasan |  |
Dr. Devaraj Ezhilarasan received his Post-Graduation and Doctoral degrees from University of
Madras and had advanced training in Hepatic Pharmacology at Université Catholique de Louvain,
Belgium on Erasmus Munus Research Award offered by Université Montpellier, France. He also
obtained his second Masters degree in Environmental Sciences from Bharathiar University,
Coimbatore, Tamil Nadu. Presently he is working as Professor of Pharmacology at Saveetha Dental
College and Hospitals, Saveetha Deemed University, Chennai and holds the position of Member-
Secretary of the Institutional Animal Ethics Committee, Biomedical Research Unit and Lab Animal
Centre (BRULAC). As a CPCSEA nominee, he participates in the Institutional Animal Ethics
Committee of a few institutions of Tamil Nadu since 2016. He is also a Senior Scientist in the Molecular and Toxicology
Division of the Blue Lab of the institution and takes care of researches done there. He received DST-INSPIRE Fellowship
offered by Govt. of India and has to his credit more than 150 research papers in high impact journals and 15 book chapters
besides being in the 'Top 2% of International Scientists Ranking List' compiled by Stanford University, USA. |
| Dr. Ethirajan Sukumar |  |
Dr. Ethirajan Sukumar is the former Dean of Research in Saveetha Deemed University, Chennai and
is currently Research Advisor, VPro Biotech, Puducherry. Prior to this, he worked as a Scientist in
Central Council for Research in Ayurveda and Siddha (Govt. of India) for more than 26 years and was
also a Visiting Faculty to some Colleges. He served as an Assistant Professor in the Department of
Applied Sciences at Higher College of Technology (University of Technology & Applied Sciences),
Muscat (Sultanate of Oman) for eight years. He holds two Master degrees and obtained PhD from
University of Madras for his research on the Medicinal Plants used in the Indigenous Medicines. He
had a Post-Doctoral stint at University of Virginia, USA and during his professional career spanning
more than 40 years, did noteworthy research on Medicinal Plants, Indigenous Medical Formulations, Active Phytochemicals,
Metallic Drugs, Chemotaxonomy, Toxicology, Environmental Pollution and Traditional Foods and published over 90 research
papers in leading indexed journals. He also served as Research Ofcer in Tamil Nadu Medicinal Plant Farms and Herbal
Medicine Corporation on deputation. During 2017-'22, he was the Member-Secretary of the Institutional Animal Ethics
Committee, Biomedical Research Unit and Laboratory Animal Center of Saveetha Dental College & Hospitals (under
Saveetha Deemed University), Chennai. |
Book Description
Laboratory animals play vital role in studying new drugs/vaccines/appliances used in the medical eld prior to Clinical trial stage. They are also employed in testing licensed products manufactured by industries for medical use. Though there are wide range of Laboratory animals, only a few species such as mice, rats, hamsters, guinea pigs and rabbits are frequently used in experiments. The use of animals in experiments is governed by the rules and regulations framed by concerned Ministry of the Government in each Country. In India, the Ministry of Environment, Forests and Climate changes has constituted an agency in its fold named “Committee for the Purpose of Control and Supervision of Experiments in Animals” (CPCSEA) under the Prevention of Cruelty to Animals Act, 1960 to monitor animal investigations in educational institutions, research organizations, industries and specialized laboratories. CPCSEA is governed by Ministry of Fisheries, Animal Husbandry and Dairying from June 2019. From January 2023 the CPCSEA has been renamed as CCSEA (Committee for control and supervision of experiments on animals) and governed by Ministry of Fisheries, Animal Husbandry and Dairying. In short the regulatory aspects are directed towards 5 R viz. Reduction - Renement- Replacement - Reuse - Rehabilitation. Though standard text books, manuals, regulatory guidelines are available for reference, a compilation with chapters and Standard Operating Procedures (S.O.Ps), covering overall activities of Laboratory Animal Facility is a long-felt need of the stake holders. Through this compilation titled “Laboratory Animals and Experimentation”, such an attempt has been made, consisting of Part-I covering chapters related to Animals used for experiments, Animal Facility and Animal Experimentation including Regulatory aspect and Part-II covering Standard Operating Procedures (S.O.P) for Animal House up-keep and maintenance, breeding and maintenance of animals, experimentation etc., as per regulatory norms. A list of references and websites are given wherever needed in the text as well as at the end of all chapters for future reading. It is emphasized that care and welfare of animals are paramount to good experimental outcome. The personnel involved in animal experimentation should strictly follow the laid down norms and ethical considerations in using animals for their research and treat them with utmost care and compassion they deserve.
