SOCIAL SCIENCE AND HUMANITIES
Advance Medicinal Synthesis: Benzazepines Vol. Ii
by Dr. Aditi
ISBN Number : 978-1-73032-013-2
Authors Details
Author Name | Image | About Author |
---|---|---|
Dr. Aditi | Dr. Aditi has been associated with academic and research activities for
more than a decad. She earned her PhD in chemistry from Banasthali
Vidhyapeeth ,Niwai ,Rajasthan. She has been an active and dynamic
person as Assistant Professor, Dept. Of Chemistry, Khalsa College for
Women, Civil Lines, Ludhiana, Punjab.As an academician she has
taught Undergraduate & Postgraduate students in different institutions.
Dr. Aditi has written no of research papers , published internationally
and she is also affiliated with various apex research bodies nationally as
well as internationally. |
Book Description
The broad spectrum of biological properties associated with oxadiazole, triazole, pyrazole, indole and azaquinazoline annulated benzazepine derivatives explained in "Advance Medicinal Synthesis: Benzazepines Vol. I" has triggered the development of new methods for the synthesis of another class of benzazepine derivatives annulated with pyrazole, isoxazole, pyrimide, 1,5- (benzodiazepine, benzothiazepine and benzoxazepine). An impressive armoury of synthetic strategies has been devised in C “Advance Medicinal Synthesis: Benzazepines Vol. II" for these class of compounds. In addition to this, an efficient protocol to the synthesis of face 'd' pyrido condensed benzazepines and its annulation with thiazolidine, tetrazole, triazole and quinazoline rings has also been devised. An alternate strategy leading to the synthesis of 2- hetrylamino and 2-sulphonamido substituted analogues of the face 'd' pyrido condensed bennzazepines of medicinal interest has also made possible by deactivation of pyridine tertiary nitrogan atom towards reaction with CH I by its conversion to its N-Oxide deriva- 3 tive with m-CPBA.